Breathing Motion: Capture, Representation, and Modelling

TNT members involved in this project:
Prof. Dr.-Ing. Jörn Ostermann
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Breathing and heart beat cause high-amplitude cyclic dislocation and deformation of organs in the human body. Both types of motion are interesting in itself, since they express physiological important functions but they are also the cause of image reconstruction artefacts, location insecurity in interventions and other problems in medical diagnosis and therapy. On the other hand, state of the art medical imaging equipment is able to capture cardiac and breathing motion (e.g. cardiac or breathing gated CT) and allows therefore capturing the patient individual motion patterns. Once a patient individual motion field (i.e. voxel dislocation vectors from one motion phase point to the next one) is extracted, it can be used for motion compensated reconstruction (of e.g. PET, SPECT, and CT images), the extraction of patient individual safety margins for radio therapy planning, or motion compensated minimal invasive interventions. The project is done in cooperation with Philips Research Europe - Hamburg.

A first goal is to develop methods for the extraction of breathing motion fields from medical image data followed by a detailed analysis of the obtained motion fields. The analysis builds the basis for further activities, e.g., developing compact motion representations and motion modeling. From a modeling perspective, one challenging task is to not only focus on patient-specific motion models but also generate inter-subject models.

Motion fields are extracted using a shape constrained deformable model approach being also to account for discontinuities in organ motion but on the same time fast and accurate. Motion model generation is carried out by the use of adequate reference structures.

Show recent publications only
  • Conference Contributions
    • Tobias Klinder, Cristian Lorenz, Jörn Ostermann
      Free-Breathing Intra- and Intersubject Respiratory Motion Capturing, Modeling, and Prediction
      SPIE 2009, SPIE Medical Imaging, Orlando, Florida, USA , February 2009
    • Udo van Stevendaal, Tobias Klinder, Cristian Lorenz, Thomas Köhler
      Breathing-Motion Correction for Helical CT
      IEEE NSS/MIC, IEEE Nuclear Science Symposium and Medical Imaging Conference, Dresden, Germany, October 2008
    • Tobias Klinder, Cristian Lorenz, Jörn Ostermann
      Respiratory Motion Modeling and Estimation
      The First Annual Workshop on Pulmonary Image Analysis, MICCAI 2008, Medical Image Computing and Computer Assisted Intervention, New York, USA, September 2008
    • Jalda Dworzak, Hans Lamecker, Jens von Berg, Tobias Klinder, Cristian Lorenz, Dagmar Kainmüller, Heiko Seim, Hans-Christian Hege, Stefan Zachow
      Towards Model-based 3-D Reconstruction of the Human Rib Cage from Radiographs
      CURAC 2008, Computer- und Roboterassistierte Chirurgie e.V., September 2008
    • Tobias Klinder, Cristian Lorenz, Jens von Berg, Steffen Renisch, Thomas Blaffert, Jörn Ostermann
      4DCT Image-Based Lung Motion Field Extraction and Analysis
      SPIE 2008, SPIE Medical Imaging, San Diego, California, USA , February 2008
    • Thomas Blaffert, Hans Barschdorff, Jens von Berg, Sebastian Dries, Astrid Franz, Tobias Klinder, Cristian Lorenz, Steffen Renisch, Rafael Wiemker
      Lung Lobe Modeling and Segmentation with Individualized Surface Meshes
      SPIE 2008, SPIE Medical Imaging, San Diego, California, USA, February 2008
    • Torbjörn Vik, Sven Kabus, Jens von Berg, Konstantin Ens, Sebastian Dries, Tobias Klinder, Cristian Lorenz
      Validation and Comparison of Registration Methods for Free-Breathing 4D Lung-CT
      SPIE 2008, SPIE Medical Imaging, San Diego, California, USA , February 2008
    • Tobias Klinder, Cristian Lorenz, Jens von Berg, Sebastian Dries, Thomas Bülow, Jörn Ostermann
      Automated Model-Based Rib Cage Segmentation and Labeling in CT images
      MICCAI 2007, Medical Image Computing and Computer Assisted Intervention, Springer, Brisbane, Australia, October 2007
    • Tobias Klinder, Cristian Lorenz, Jens von Berg
      Geometrical Rib-Cage Modeling, Detection, and Segmentation
      CARS 2007, Computer Assisted Radiology and Surgery, Berlin, Germany, June 2007