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Coding of Sequencing Data

TNT members involved in this project:
Dr.-Ing. Marco Munderloh
Prof. Dr.-Ing. Jörn Ostermann
Dipl.-Ing. Jan Voges

Over the past years technological advances in sequencing - the process of reading out genomic information from biological samples - have led to a faster and more cost-efficient approach to sequence individual genomes and other genomic samples. Because of the enormous amount of sequencing data generated the processing, storage and analysis of sequencing data entails novel challenges for the scientific community. New processes and tools have to be developed to overcome the current limitations in terms of storage space, processing speed and many more. Our goal is to develop novel algorithms to enhance data processing "from the tissue to the hard drive".

In the scope of this project we actively contribute to the development of the MPEG-G standard (ISO/IEC 23092). More information is available on the MPEG-G website.

If you are interested in writing your thesis and thereby in contributing to this project please contact Jan Voges.

  • Jan Voges, Jörn Ostermann: Streaming für die Genomforschung, Binaire, Ausgabe 2/2019 (link)

Show all publications
  • Brian E Bliss, Joshua M Allen, Saurabh Baheti, Matthew A Bockol, Shubham Chandak, Jaime Delgado, Jan Fostier, Josep L Gelpi, Steven N Hart, Mikel Hernaez Arrazola, Matthew E Hudson, Michael T Kalmbach, Eric W Klee, Liudmila S Mainzer, Fabian Müntefering, Daniel Naro, Idoia Ochoa-Alvarez, Jörn Ostermann, Tom Paridaens, Christian A Ross, Jan Voges, Eric D Wieben, Mingyu Yang, Tsachy Weissman, Mathieu Wiepert
    Genie: an MPEG-G conformant software to compress genomic data
    International Conference for High Performance Computing, Networking, Storage and Analysis (SC19), p. (poster), Denver, CO (US), November 2019
  • Dunling Li, Claudio Alberti, Jaime Delgado, Jan Voges, Itaru Kaneko, Marco Mattavelli, Patrick Cheung, Paolo Ribeca
    MPEG-G Best Practices Deployment Guide
    ISO/IEC JTC 1/SC 29/WG 11, Document Number M50913, Geneva (CH), October 2019
  • Christian Rohlfing, Viktor Tunev, Jan Voges
    Proposed Updates to the MPEG-G Genomic Information Database
    ISO/IEC JTC 1/SC 29/WG 11, Document Number M51192, Geneva (CH), October 2019